The Science and Business of Drug Discovery by Edward D. Zanders

Author:Edward D. Zanders
Language: eng
Format: epub
ISBN: 9783030578145
Publisher: Springer International Publishing

A maximum of around 200 compounds tested. Often these are not small molecules picked at random but highly biased towards a defined chemical structure such as those used for focused compound libraries or for fragment-based screening (Chap. 7). It is also possible that the screening target is difficult to set up for more than a few tests, a situation that arises when screening whole tissues or organs. Because the number of tests is low, there is normally no requirement for automation.Medium throughput.

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